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Index > Protein center > SLURP1(Gene name) > Human
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  • SLURP1 (Gene name),
  • Secreted Ly-6/uPAR-related protein 1 (Protein name ),  SLUR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SLURP1(ARS);
    Protein name:
    Secreted Ly-6/uPAR-related protein 1(SLURP-1);
    Alternative:
    ARS(component B)-81/S;ARS component B;Anti-neoplastic urinary protein(ANUP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    103
    Sequence:
    50:
    MASRWAVQLL | LVAAWSMGCG | EALKCYTCKE | PMTSASCRTI | TRCKPEDTAC | 
    100:
    MTTLVTVEAE | YPFNQSPVVT | RSCSSSCVAT | DPDSIGAAHL | IFCCFRDLCN | 
    103:
    SEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human SLURP-1
    Cat.:
    E15535h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human SLURP-1
    Cat.:
    E15535m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SLURP-1
    Cat.:
    U15535m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SLURP-1
    Cat.:
    U15535h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human SLURP-1
    Cat.:
    P15535Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SLURP-1
    Cat.:
    P15535Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human SLURP-1
    Monoclonal Antibody for Human SLURP-1
    Protein for Human SLURP-1
    Protein for Human SLURP-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      Mastrangeli R.
      Submitted (1996-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Placenta.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Skin.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes."
      Ridge R.J. , Sloane N.H.
      Cytokine8:1-5(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
      tissue: Granulocyte.
    5. 5.
      "Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily."
      Andermann K. , Wattler F. , Wattler S. , Heine G. , Meyer M. , Forssmann W.-G. , Nehls M.
      Protein Sci.8:810-819(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;SIGNAL SEQUENCE CLEAVAGE SITE
    6. 6.
      "ARS component B: structural characterization, tissue expression and regulation of the gene and protein (SLURP-1) associated with Mal de Meleda."
      Mastrangeli R. , Donini S. , Kelton C.A. , He C. , Bressan A. , Milazzo F. , Ciolli V. , Borrelli F. , Martelli F. , Biffoni M. , Serlupi-Crescenzi O. , Serani S. , Micangeli E. , El Tayar N. , Vaccaro R. , Renda T. , Lisciani R. , Rossi M. , more...
      Eur. J. Dermatol.13:560-570(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION;POSSIBLE FUNCTION
    7. 7.
      "SLURP1 is a late marker of epidermal differentiation and is absent in Mal de Meleda."
      Favre B. , Plantard L. , Aeschbach L. , Brakch N. , Christen-Zaech S. , de Viragh P.A. , Sergeant A. , Huber M. , Hohl D.
      J. Invest. Dermatol.127:301-308(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;POSSIBLE FUNCTION;VARIANT MDM HIS-71;CHARACTERIZATION OF VARIANTS MDM ARG-15 AND ARG-86
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MDM
    9. 9.
      "Mal de Meleda (MDM) caused by mutations in the gene for SLURP-1 in patients from Germany, Turkey, Palestine, and the United Arab Emirates."
      Eckl K.M. , Stevens H.P. , Lestringant G.G. , Westenberger-Treumann M. , Traupe H. , Hinz B. , Frossard P.M. , Stadler R. , Leigh I.M. , Nuernberg P. , Reis A. , Hennies H.C.
      Hum. Genet.112:50-56(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MDM ARG-15 AND ARG-86
    10. 10.
      "Heterozygous manifestations in female carriers of Mal de Meleda."
      Mokni M. , Charfeddine C. , Ben Mously R. , Baccouche D. , Kaabi B. , Ben Osman A. , Dellagi K. , Abdelhak S.
      Clin. Genet.65:244-246(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MDM ARG-77 AND TYR-99
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